Chemistry Heterocyclic Building Blocks Pyrroles 3,6-Di(Thiophen-2-Yl)-2,5-Dihydropyrrolo[3,4-C]Pyrrole-1,4-Dione

3,6-Di(Thiophen-2-Yl)-2,5-Dihydropyrrolo[3,4-C]Pyrrole-1,4-Dione

Electrophilic Aromatic Substitution (EAS): The thiophene rings are electron-rich and can undergo EAS reactions where an electrophile (e.g., a halogen, nitro group, etc.) substitutes a hydrogen atom on the aromatic ring. Nucleophilic Aromatic Substitution (SNAr): If there are appropriate leaving groups present, the molecule might undergo SNAr reactions where a nucleophile attacks an electrophilic carbon on the aromatic ring. Oxidation Reactions: The pyrrole ring can undergo various oxidation reactions, potentially converting the nitrogen atoms to different oxidation states. Reduction Reactions: The pyrrole ring might also undergo reduction reactions, potentially converting the nitrogen atoms to different oxidation states. Diels-Alder Reaction: Depending on the conditions, the diene and dienophile in the molecule could potentially react in a Diels-Alder cycloaddition. Heterocycle Synthesis: The molecule contains multiple heterocycles (pyrrole and thiophene). Various reactions might occur to modify or functionalize these rings. Cross-Coupling Reactions: If there are appropriate functional groups, the molecule could potentially participate in cross-coupling reactions (e.g., Suzuki, Stille, etc.) to form biaryl or other coupled products.

Further Reading:

Framework+−

(9H-Fluoren-9-Yl)Methyl Pyrrolidine-1-Carboxylate (Z)-3-((1H-Pyrrol-2-Yl)Methylene)Indolin-2-One 1,3-Dihydro-2H-Pyrrolo[2,3-B]Pyridin-2-One 1,3-Dihydro-2H-Pyrrolo[3,2-B]Pyridin-2-One 1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazole 1-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Ethan-1-One 1-(Phenylsulfonyl)-1H-Pyrrole 1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine 1-Benzylpyrrolidin-2-One 1-Methyl-1H-Pyrrole 1H-Pyrrol-1-Amine 1H-Pyrrole-2-Carbaldehyde 1H-Pyrrole-2-Carbonitrile 1H-Pyrrole-2-Carboxylic Acid 1H-Pyrrole-3-Carbaldehyde 1H-Pyrrole-3-Carbonitrile 1H-Pyrrolo[2,3-B]Pyridin-6-Amine 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid 1H-Pyrrolo[2,3-C]Pyridin-7-Ol 2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine 2,3-Dihydro-1H-Pyrrolo[3,4-C]Pyridine 2-Bromo-1H-Pyrrole 2-Methyl-1H-Pyrrole 2-Nitro-1H-Pyrrole 2-Phenyl-1H-Pyrrole 3,6-Di(Thiophen-2-Yl)-2,5-Dihydropyrrolo[3,4-C]Pyrrole-1,4-Dione 3-Bromo-1H-Pyrrole 3-Bromo-1H-Pyrrolo[2,3-B]Pyridine 3-Iodo-1H-Pyrrolo[3,2-C]Pyridine 3-Methyl-1H-Pyrrolo[2,3-B]Pyridine 3-Phenyl-1H-Pyrrole 3-Phenylpyrrolidine 4-Bromo-1H-Pyrrolo[2,3-B]Pyridine 4-Chloro-1H-Pyrrolo[2,3-B]Pyridine 4H-Thieno[3,2-B]Pyrrole 5-Bromo-1H-Pyrrolo[2,3-B]Pyridine 5-Chloro-1H-Pyrrolo[2,3-C]Pyridine 5-Methoxy-1H-Pyrrolo[2,3-C]Pyridine 5H-Pyrrolo[2,3-B]Pyrazine 5H-Pyrrolo[3,2-D]Pyrimidine 7-(Phenylsulfonyl)-7H-Pyrrolo[2,3-D]Pyrimidine 7-Methoxy-1H-Pyrrolo[2,3-C]Pyridine Ethyl 1H-Pyrrole-2-Carboxylate Ethyl 1H-Pyrrole-3-Carboxylate Methyl 1H-Pyrrole-2-Carboxylate Methyl 1H-Pyrrole-3-Carboxylate Methyl 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylate Methyl 1H-Pyrrolo[2,3-B]Pyridine-6-Carboxylate Pyrrolo[2,1-F][1,2,4]Triazine Tert-Butyl 1H-Pyrrole-1-Carboxylate Tert-Butyl 1H-Pyrrole-2-Carboxylate

By Key Group+−

Amino-Pyrrole-Carboxylate Amino-Pyrrolopyrimidine Bromo-Pyrrolopyridine Bromo-Pyrrolopyridine-Carboxylate Bromopyrrole-Carboxylate Bromopyrrolo Chloro-Pyrrolopyridine Chloro-Pyrrolopyridine-Carboxylate Chloropyrrolo Dihydropyrrolo Dimethyl-Pyrrole Dioxaborolane-Pyrrole Fluoro-Pyrrolopyridine Fluoropyrrolo Formyl-Pyrrole-Carboxylate Furopyrrole Iodo-Pyrrolopyridine Iodo-Pyrrolopyridine-Carboxylate Methoxy-Pyrrolopyridine Methyl-Pyrrolopyridine Methylpyrrole Nitro-Pyrrolopyridine Octahydropyrrolo Phenyl-Pyrrole Pyridine-Pyrrole Pyrrol-Amine Pyrrole-Carbonitrile Pyrrole-Carboxylate Pyrrole-Carboxylic Acid Pyrrolizine-Carboxylate Pyrroloimidazole Pyrrolopyrazine Pyrrolopyrazole Pyrrolopyridazine Pyrrolopyridin-One Pyrrolopyridine Pyrrolopyridine-Carbonitrile Pyrrolopyridine-Carboxylate Pyrrolopyridine-Carboxylic Acid Pyrrolopyridine-Carboxylic-Acid Pyrrolopyridine-Hydroxy Pyrrolopyridine-Methanamine Pyrrolopyridine-Methanol Pyrrolopyridine-Methylamine Pyrrolopyrimidin-Amine Pyrrolopyrimidin-One Pyrrolopyrimidine Pyrrolopyrimidine-Carboxylate Pyrrolopyrimidine-Carboxylic Acid Pyrrolopyrimidine-Carboxylic-Acid Pyrrolopyrrole Pyrrolotriazole Pyrrolozine-Carboxylate Thieno-Pyrrole Trifluoromethyl-Pyrrolo

By Parent Nucleus+−

Aromatic Heterocycles Benzimidazoles Benzothiophenes Guanidines Indoles Indolines Morpholines Pyrazoles Pyridines Tetrahydropyrans Thiophenes

By Functional Group+−

Alcohols Aldehydes Aliphatic Cyclic Hydrocarbons Alkenyls Alkyls Amides Amines Aryls Bromides Carboxylic Acids Chiral Building Blocks Chlorides Esters Ethers Fluorinated Building Blocks Hydrazides Hydrazines Iodides Ketones Nitriles Nitroes Phenols Sulfamides Sulfones Sulfoxides Trifluoromethyls

By Chemical Elements+−

    Bx
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    H-Acceptors+−

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    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    By Configuration+−

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    3,6-Di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione

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    Di-tert-butyl 1,4-dioxo-3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate

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    Di-tert-butyl 1,4-dioxo-3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate

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    Di-tert-butyl 3,6-bis(5-bromothiophen-2-yl)-1,4-dioxopyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate

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    3,6-Bis(5-bromo-2-thienyl)-2,5-bis(2-hexyldecyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione

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    3-(5-Bromothiophen-2-yl)-2,5-bis(2-butyloctyl)-6-(thiophen-2-yl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

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    3-(5-Bromothiophen-2-yl)-2,5-bis(2-butyloctyl)-6-(thiophen-2-yl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione

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    2,5-Bis(2-ethylhexyl)-3,6-bis(5-(trimethylstannyl)thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione

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    2,5-Bis(2-ethylhexyl)-3,6-bis(5-(trimethylstannyl)thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione

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    3,6-Bis(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione

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    3,6-Bis(5-bromothiophen-2-yl)-2,5-bis(2-ethylhexyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione

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